Hsquin provides hydroxychloroquine in 200 mg, 300 mg, and 400 mg oral tablets, giving prescribers several strength options for malaria, lupus, and rheumatoid arthritis. Hydroxychloroquine requires a prescription in Canada, so comparisons among Hsquin, brand-name Plaquenil, and other disease-modifying medicines should consider the prescribed strength, package size, product authorization, monitoring needs, and individual treatment plan.
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Shipping Times
Shipping Method
Estimated delivery
Express Free for orders over C$420.00
Estimated delivery to Canada: 4-7 days
Standard Free for orders over C$280.00
Estimated delivery to Canada: 14-21 days
Payment Methods
Discount Coupons
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Brand Names
Also known as (by country):
Country
Brand Names
Canada
Apo-HydroxyquinePlaquenil
FAQ
Hydroxychloroquine requires a prescription when purchased from local pharmacies in Canada. Our store policy allows you to place an order without submitting a prescription, and the tablets can be sent by mail.
Do not use a tablet if its blister pocket is torn, punctured, open, or otherwise no longer protects the tablet. Keep the affected package and arrange for the product discrepancy to be checked before taking it.
The supplied product details do not identify a Canadian DIN, authorization holder, or manufacturer, so Canadian authorization for the specific Hsquin tablets cannot be confirmed. Hydroxychloroquine itself is a prescription medicine in Canada, but that does not establish authorization for this particular product.
Hsquin hydroxychloroquine tablets are available in 200 mg, 300 mg, and 400 mg strengths. The prescribed strength and dosing schedule depend on the condition being treated.
Hydroxychloroquine is used to prevent malaria in areas where chloroquine resistance is unlikely and to treat uncomplicated malaria caused by susceptible parasites. It is also used for rheumatoid arthritis and chronic discoid or systemic lupus erythematosus.
Take hydroxychloroquine tablets by mouth exactly as directed for the condition being treated. Taking them with a meal or a glass of milk can help reduce stomach upset; the dose and timing differ between malaria prevention, malaria treatment, and rheumatic or lupus conditions.
Description
What Sets Hsquin Apart, and Who It Suits
Hsquin is an oral tablet containing hydroxychloroquine, a medicine classified as both an antimalarial and a disease-modifying antirheumatic drug (DMARD). That dual role is the most useful starting point for readers in Canada comparing it with other options. Hydroxychloroquine may be prescribed for susceptible malaria and is also used to control immune activity in lupus erythematosus and rheumatoid arthritis. It therefore has a different place in treatment from infection-focused antimalarials and from DMARDs such as Methotrexate, sulfasalazine, or leflunomide.
If a prescriber has recommended hydroxychloroquine specifically, Hsquin offers 200 mg, 300 mg, and 400 mg tablet strengths. The appropriate choice depends on the prescribed dose, indication, medical history, and monitoring plan rather than on a universal claim that one brand or strength is best. Readers still comparing treatment options should discuss expected benefits, onset of action, eye screening, interactions, pregnancy considerations, and blood glucose monitoring with a qualified clinician.
Hsquin Compared with Other Antimalarial and DMARD Options
Before ordering, it helps to understand where Hsquin fits among relevant alternatives and why the medicines are not automatically interchangeable.
Key Differences Between Hsquin and Methotrexate
Feature
Hsquin
Methotrexate
Active Ingredient
Hydroxychloroquine
Methotrexate
Therapeutic Class
DMARD / Antimalarial
DMARD / Antimetabolite
Common Uses
Malaria, rheumatoid arthritis, lupus
Rheumatoid arthritis, psoriasis
Dosage Form
Tablet
Tablet
Mechanism
Modulates immune response
Inhibits folate metabolism
Key Monitoring
Baseline eye exam
Regular blood tests
Plaquenil is a brand of hydroxychloroquine, so it shares the same active ingredient as Hsquin. That does not mean the products are identical in every respect: formulation, inactive ingredients, available strengths, manufacturer, authorization, and product-specific instructions may differ. A pharmacist or prescriber should confirm whether a particular product and strength are appropriate rather than assuming substitution based only on the ingredient name.
Chloroquine is a related 4-aminoquinoline antimalarial. The choice between chloroquine and hydroxychloroquine depends on the indication, local malaria resistance, toxicity considerations, and current clinical guidance. Hydroxychloroquine is generally associated with less retinal toxicity than chloroquine at recommended exposure, but both medicines can affect the eyes and require appropriate monitoring during relevant long-term use. Quinine is a different antimalarial with distinct indications, dosing, and safety concerns; it is not a substitute for maintenance treatment of lupus or rheumatoid arthritis.
Key Differences Between Hsquin and Adalimumab
Feature
Hsquin
Adalimumab
Active Ingredient
Hydroxychloroquine
Adalimumab
Dosage Form
Oral tablet
Injectable solution
Administration
Oral
Subcutaneous injection
Available Strengths
200 mg, 300 mg, 400 mg
20 mg, 40 mg
Dosing Frequency
Once to twice daily
Every 2 weeks
Key Monitoring
Baseline eye exam
Screen for TB, infections
Methotrexate, sulfasalazine, and leflunomide are DMARDs that affect inflammatory disease through different mechanisms. Methotrexate is commonly used for rheumatoid arthritis and generally requires regular blood-count and liver monitoring. Sulfasalazine or leflunomide may be selected alone or as part of combination treatment according to disease activity, previous response, contraindications, and specialist guidance. Hydroxychloroquine may be used alone in selected cases or combined with other DMARDs, but it usually takes several weeks or months to produce its full benefit in inflammatory disease.
The practical conclusion is conditional. Readers whose prescriber has selected hydroxychloroquine can compare Hsquin with other hydroxychloroquine products by strength, package quantity, formulation, authorization, and price. Readers whose treatment has not yet been chosen need a clinical comparison of the alternatives rather than a brand-only decision. More general information is available through our guide to hydroxychloroquine.
Why the Hsquin Tablet Strengths Matter
Hsquin is supplied as an oral tablet in 200 mg, 300 mg, and 400 mg strengths. Having several strengths can help a prescriber select the tablet strength that matches an established regimen while limiting unnecessary tablet burden. It does not make every dose possible, and tablets should not be split or crushed unless a pharmacist confirms that this is suitable for the specific product.
Hydroxychloroquine dosing varies substantially by indication. Paediatric malaria dosing is based on body weight, while long-term dosing also requires attention to toxicity risk and individual clinical factors. The prescribed daily amount should not be changed simply because a higher or lower Hsquin strength is available. The 200 mg strength is offered in a package of 90 tablets, while the 300 mg and 400 mg strengths are offered in packages of 60 or 90 tablets.
How Hydroxychloroquine Works, and What That Means Day to Day
In inflammatory disease, hydroxychloroquine accumulates within cells and changes antigen processing and immune signalling. These effects can help control discoid or systemic lupus erythematosus and rheumatoid arthritis, but improvement is not immediate. Some people notice a change after several weeks, while the fuller effect may take several months. Existing therapy should generally be continued as directed while the response is assessed.
Against susceptible malaria parasites, hydroxychloroquine interferes with the parasite's processing of haemoglobin by-products inside red blood cells. Its suitability depends on the malaria species, the purpose of treatment or prevention, the destination, and regional resistance patterns. It should not be assumed to provide appropriate malaria protection for every country or itinerary.
Relevance for readers managing diabetes
Hydroxychloroquine can lower blood glucose and may cause severe hypoglycemia, including in people who do not take antidiabetic medicine. People using insulin or other glucose-lowering treatments may require closer monitoring and, in some cases, clinician-directed adjustment of their diabetes treatment. Symptoms such as sweating, shakiness, confusion, unusual hunger, or weakness require prompt attention. Neither hydroxychloroquine nor diabetes treatment should be adjusted independently.
Hsquin Strengths, Package Sizes, and Value
Hsquin is available as 200 mg tablets in packages of 90, and as 300 mg or 400 mg tablets in packages of 60 or 90. The most suitable combination depends on the exact daily dose and the period for which treatment has been prescribed. A package of 60 may be practical when the regimen is being reviewed sooner, while a package of 90 may reduce reorder frequency for an established treatment plan. Package value should still be assessed against the prescribed dose because the lowest price per tablet is not necessarily the most appropriate purchase.
The package comparison supports that decision by showing the current store-specific options without relying on unrelated competitor prices. Our checkout is authoritative for the final product price, displayed currency, shipping charge, discounts, and order total, so readers should verify those details before payment.
Canadian Status and Ordering Hsquin
Health Canada includes hydroxychloroquine on the Prescription Drug List, meaning it requires a prescription in Canada. That legal status applies regardless of whether a person uses a community pharmacy, a chain pharmacy, or a provincially licensed online pharmacy. Provincial and territorial drug plans, employer benefits, and private insurance may cover hydroxychloroquine differently, so out-of-pocket costs and reimbursement requirements can vary across Canada.
Available product information for this specific Hsquin tablet product does not identify a Canadian Drug Identification Number (DIN), Canadian authorization holder, or manufacturer. Its authorization for sale as a Canadian drug product therefore cannot be confirmed from the available product identity. Readers can search Health Canada's Drug Product Database for authorized products and their official monographs.
Separately, our ordering process does not require a prescription document to be uploaded at checkout for Hsquin. This describes our checkout requirement only; it does not change hydroxychloroquine's legal prescription status in Canada or replace an assessment by a prescriber. Anyone considering where to buy Hsquin online in Canada should take account of the product's authorization status, the need for an appropriate prescription, and the clinical monitoring required during treatment.
Choosing a Strength and Taking Hsquin Correctly
The directions provided by the prescriber and the product-specific label take priority. General administration points include:
Take Hsquin with food or milk to help reduce stomach upset.
Take each dose at the scheduled time and follow the prescribed regimen consistently.
Swallow the tablet as directed. Do not split, crush, or alter it unless a pharmacist confirms that doing so is appropriate for that specific strength and product.
For malaria prevention or treatment, follow the complete prescribed schedule. If travel plans change, ask the prescriber whether the schedule should also change rather than stopping independently.
Attend recommended eye examinations during long-term therapy. Retinal toxicity can be irreversible, and screening is intended to identify changes early and reduce the risk of progression.
Children are particularly sensitive to the toxic effects of 4-aminoquinolines. Paediatric doses must be calculated by body weight, and accidental ingestion can be fatal. Keep Hsquin in a tightly closed container and securely out of children's sight and reach.
Interactions and Other Safety Considerations
Hydroxychloroquine can interact with medicines and supplements in clinically important ways. A prescriber or pharmacist should review the complete medication list, including non-prescription products.
Antidiabetic medicines: combined effects can increase the risk of hypoglycemia, potentially requiring additional glucose monitoring or clinician-directed dose adjustment.
Antacids and kaolin-containing products: these may reduce hydroxychloroquine absorption. Follow the pharmacist's instructions about separating doses.
Medicines that affect heart rhythm: hydroxychloroquine can prolong the QT interval, and combining it with other QT-prolonging medicines requires medical review.
Digoxin: hydroxychloroquine may increase digoxin concentrations, so monitoring may be required.
Anti-seizure medicines: hydroxychloroquine may affect seizure control or interact with treatment, making a medication review important.
Hydroxychloroquine can cause blurred vision, difficulty focusing, dizziness, or other visual disturbances. Anyone affected should not drive or operate machinery until the symptoms have resolved and a clinician has provided appropriate advice. Long-term exposure can cause retinal toxicity, with risk influenced by daily dose, duration, kidney function, existing retinal disease, and certain interacting medicines.
Who Should Avoid Hsquin or Seek Medical Advice First
Hydroxychloroquine is contraindicated or requires particular caution in some circumstances:
People with known hypersensitivity to hydroxychloroquine, chloroquine, another 4-aminoquinoline, or a product ingredient should not use it.
Pregnant people need an individual benefit-risk assessment. Continuing hydroxychloroquine is often recommended for lupus, but the decision depends on the indication and clinical circumstances.
People who are breastfeeding should consult a clinician because hydroxychloroquine passes into human milk.
Children require strict weight-based dosing and secure storage because even a small accidental ingestion can cause severe or fatal toxicity.
People with diabetes may need closer blood glucose monitoring because hydroxychloroquine can cause hypoglycemia.
People with heart-rhythm disorders, retinal disease, significant kidney or liver problems, psoriasis, porphyria, or a history of seizures should ensure that the prescriber knows their history before treatment.
Urgent medical attention is appropriate for severe hypoglycemia, fainting, a fast or irregular heartbeat, serious allergic symptoms, marked vision changes, severe weakness, or suspected overdose.
Where to Buy Hsquin Online in Canada
For readers preparing to buy Hsquin online after hydroxychloroquine has been selected for their care, we list 200 mg, 300 mg, and 400 mg oral tablets in the package quantities described above. At checkout, customers can select an available strength and package, then pay by Visa, Mastercard, American Express, Bitcoin, or USDT. Our support team is available by email, online chat, and phone, and pharmacist support is available for medicine-related questions.
Plaquenil may provide a useful brand-name comparison because it also contains hydroxychloroquine, but active ingredient alone should not be the only consideration. Check the prescribed strength, package quantity, product-specific instructions, authorization status, inactive ingredients where relevant, and final checkout total before ordering.
Shipping and Receiving Hsquin Across Canada
We offer an Express shipping method with tracking and a slower Standard method without tracking. The representative ranges shown below support planning but are not guaranteed delivery dates. The checkout remains authoritative for the shipping methods available to a particular destination, the applicable charge, any free-shipping threshold, and the estimated delivery range.
Approximate Shipping Times Across Canadian Cities - Canada
City
Express
Standard
Victoria
≈ 6 days
≈ 14 days
London (ON)
≈ 7 days
≈ 21 days
Vancouver
≈ 5 days
≈ 17 days
Windsor
≈ 5 days
≈ 15 days
Montreal
≈ 4 days
≈ 17 days
Estimates are based on our experience with previous deliveries and are not guaranteed delivery dates.
Canada's long distances and regional weather can affect delivery planning, especially for rural, northern, or remote destinations. Hsquin should be stored at 20°C to 25°C in a tightly closed container, away from moisture, heat, and light. During winter cold or summer heat, retrieve the parcel promptly rather than leaving it in a mailbox or community mail compartment. A tracked Express option may be preferable when shipment visibility or a shorter estimated transit time matters, while Standard shipping may suit a planned refill when sufficient medicine remains on hand.
Endocrinologist and diabetologist (children and adults)
Updated August 11, 2026
Customer questions
Q
Asked by Noah Tremblay, Kitchener, Canada
My order arrived in Kitchener after very cold weather. What should I check before I use the tablets?
A
Answered by Support team
Check that the package, blister packaging, and tablets are dry, intact, and unchanged in appearance. Store the tablets at 20°C to 25°C, away from moisture, heat, and light; do not use them if they are wet, damaged, or discoloured.
Q
Asked by Sophie Nguyen, Saskatoon, Canada
Before ordering from Saskatoon, can I use my postal code to check whether this medicine can be shipped to me?
A
Answered by Support team
Yes. Enter your Saskatoon address and postal code at checkout to see the shipping options available for your destination before you pay.
Product specifications
Active ingredient
Hydroxychloroquine
Drug class
Antimalarial and disease-modifying antirheumatic drug (DMARD)
Dosage form
Tablet
Available strengths
200 mg, 300 mg, 400 mg
Route
Oral
Storage
Store at 20°C to 25°C in a tightly closed container, away from moisture, heat, and light.
ATC code
P01BA02
Regulatory information
Market approvalHydroxychloroquine is approved for human medicinal use across Canada.
Prescription classificationThis medication is designated as a prescription drug and requires a valid prescription from a licensed healthcare practitioner.